THE PURE EP™ PLATFORM

Revitalizing the Power 
of Unipolar Signals 

Revitalizing the Power 
of Unipolar Signals 

Despite the growing body of pre-clinical evidence validating the efficacy of unipolar signal modification to guide catheter ablation,1 accurate and reliable unipolar signal data has been limited by conventional, outdated technologies.

Until now...

A New Era of Possibility in the 
Field of Electrophysiology

Research studies from Cleveland Clinic validate the ability of PURE EP™ to deliver clear, trusted unipolar signals, revealing a 66% reduction in procedure time while maintaining accuracy in lesion spacing and placement  vs. the conventional ablation index (AI).2,3,4

Heart Rhythm journal

Unipolar Signal Modification-Guided Radiofrequency Ablation

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Heart Rhythm journal

Feasibility of Unipolar Signal Guided Ablation in Creating Contiguous Lines of Conduction Block: A Proof-of-Concept Study

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Heart Rhythm journal

Comparison of Unipolar Electrogram Monitoring During Radiofrequency Ablation in Viable and Ablated Myocardium: Loss of the S-component

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Harnessing the Power of Automation

Only available on the PURE EP™ Platform, Near Field Tracking (NFT) monitors changes in the local unipolar electrogram, empowering EPs with tissue-specific feedback and characterization in real time.

"Leveraging PURE EP™'s unipolar signals to assess lesion efficiency can increase confidence when you’re trying to pinpoint that critical ablation site… An invaluable tool that enhances workflow and potentially reduces procedural time."

-Hicham El Masry, MD, FHRS (Assistant Professor, Mayo Clinic Arizona)

Reimagine What's Possible  in Cardiac Care

Reimagine What's Possible in Cardiac Care

With access to the latest advancements in electrophysiology, the PURE EP™ Platform delivers a suite of configurable applications that elevate what's possible in EP labs. Explore cases, presentations and papers for firsthand physician accounts.

Explore physician insights
1. Edzards, M., et al. (2019, December). Frequency bandwidth comparative testing using a novel signal processing platform in a controlled bench top setting. ©BioSig Technologies, Inc. Rev A2.1.01 2020[27].
2. Tabaja, C., et al. (2023, May). PO-01-200 Unipolar Signal Modification-Guided Radiofrequency Ablation. [Abstract]. Heart Rhythm 2023, New Orleans, LA. 20(5): S187. DOI: https://doi.org/10.1016/j.hrthm.2023.03.576.
3. Tanaka-Esposito, C., et al. (2023, May). PO-03-037 Feasibility of Unipolar Signal Guided Ablation in Creating Contiguous Lines of Conduction Block: A Proof-of-Concept Study [Abstract]. Heart Rhythm 2023, New Orleans, LA. 20(5): S448-S449. DOI: https://doi.org/10.1016/j.hrthm.2023.03.985.
4. Yavin, H., et al. (2023, May). PO-02-002 Comparison of Unipolar Electrogram Monitoring during Radiofrequency Ablation in Viable and Ablated Myocardium: Loss of the S-component [Abstract]. Heart Rhythm 2023, New Orleans, LA. 20(5): S324-325. DOI: https://doi.org/10.1016/j.hrthm.2023.03.762.